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Published as a conference paper at NeurIPS 2026

From Persistence to Survival: Hypothesis Testing, Effect Sizes and Vectorisation for Topological Features

Juliette Murris, Bernadette J Stolz, Karsten Borgwardt

Abstract

Persistence diagrams are common representations in topological data analysis, yet they lack both the vector space structure required by machine learning algorithms and a principled framework for statistical comparison. We introduce STRAND (Survival Topological Representation ANalysis of Diagrams), which treats (collections of) PDs as survival data: each topological feature with persistence value is a fully observed time-to-event, and the persistence survival function is the central object for comparing diagrams. From this single representation we derive (i) a non-parametric two-sample test with calibrated Type I error and high power from a small number of diagrams; (ii) interpretable effect sizes; and (iii) a 1-Wasserstein-stable feature vector for downstream machine learning. We validate calibration and power on synthetic manifolds with controlled topology, demonstrate competitive vectorisation across 14 graph and 3D point cloud benchmarks, and apply the method to study functional brain connectivity in fMRI/neuroscience data. To our knowledge, STRAND is the first method to provide hypothesis testing and vectorisation for persistence diagrams from a single coherent and interpretable representation.

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