acceptodds
Under review as a conference paper at ICLR 2027

ViSTA: A Simple Bridge Extends Visual Alignment to Clinical Time-Series Understanding in Multimodal LLMs

Abstract

Clinical prediction models estimate risk from patient measurements, while large language models support medical text understanding and question answering. Yet their language capabilities do not ensure accurate prediction from structured, high-dimensional clinical time series. Improving this ability would connect risk estimation with flexible questions about a patient's evolving condition. We introduce , a compact adapter that incorporates irregular numerical measurements into a pretrained vision-language model's chart representations. It learns corrections to visual tokens while leaving all pretrained parameters unchanged. On MIMIC-IV, has the highest mean scores among the compared adaptations on all four metrics for acute kidney injury and mortality prediction across models with 2-9 billion parameters. With 0.516 million trainable parameters, the 2-billion-parameter model reaches an area under the ROC curve of 0.7376 for acute kidney injury, compared with GPT-5.6 Sol's 0.7380 with text input and high reasoning effort. Training for temporal question answering yields 69.27% accuracy at 4 billion parameters with over 90% fewer trainable parameters than low-rank adaptation using charts or numerical text, at a 2.82-4.88 percentage-point accuracy gap. extends pretrained language models to numerical prediction and temporal questions.

open until 14 Dec 2026

est. 32% chance this paper gets accepted at ICLR 2027.

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